TRIAZOLAM 0.25mg


Triazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used short term (7 to 10 days) to treat insomnia (trouble falling or staying asleep).

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Triazolam : Halcion, Hypam, Apo-Triazo, Trilam

Triazolam  is a drug that is used to promote sleep in individuals who have difficulty sleeping (insomnia). It is in the benzodiazepine family of drugs, the same family that includes diazepam (Valium), alprazolam (Xanax), clonazepam (Klonopin), flurazepam (Dalmane), lorazepam (Ativan), and others. Insomnia is believed often to be the result of anxiety, a state in which the brain is excessively active. Gamma-aminobutyric acid (GABA) is a substance produced in the brain which inhibits (slows down) nerves and many of the activities of the brain. Triazolam and other benzodiazepines enhance the effects of GABA and thereby reduce activity in the brain and promote sleep. Triazolam was approved by the FDA in 1982

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Triazolam (Halcion) is a prescription medication used to treat short-term insomnia. Side effects, drug interactions, dosing and storage, and pregnancy safety should be reviewed prior to taking this medication.

IMPORTANT INFORMATION:
Source: https://www.drugs.com/mtm/triazolam.html
You should not use this medicine if you are allergic to triazolam or similar medicines (such as alprazolam, diazepam, lorazepam, Valium, Xanax, Versed, Klonopin, and others).

Some drugs should not be used with triazolam. Your treatment plan may change if you also use:

  • nefazodone;

  • cancer medicine;

  • an antibiotic or antifungal medicine; or

  • antiviral medicine to treat HIV or hepatitis C.

Tell your doctor if you have ever had:

  • depression, mental illness, suicidal thoughts or actions;

  • lung disease, breathing problems, sleep apnea (breathing stops during sleep); or

  • alcoholism or drug addiction.

If you use triazolam during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

You should not breastfeed within 28 hours after using triazolam. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

If you do breastfeed, tell your doctor if you notice drowsiness, breathing problems, or feeding problems in the nursing baby.

Not approved for use by anyone younger than 18 years old.



HOW TO USE TRIAZOLAM
Source: https://www.webmd.com/drugs/2/drug-11213/triazolam-oral/details
Read the Medication Guide provided by your pharmacist before you start using triazolam and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually just before you get into bed. The dosage is based on your medical condition, age, and response to treatment.

Although unlikely, this drug can rarely cause temporary short-term memory loss. To lessen the chance of this, do not take a dose of this drug unless you have time for a full night's sleep of at least 7 to 8 hours. If you have to wake up before that, you may have some memory loss.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if your condition lasts after 7 to 10 days, or if it gets worse.

You may have trouble sleeping the first few nights after you stop taking this medication. This is called rebound insomnia and is normal. It will usually go away after 1 or 2 nights. If this effect continues, contact your doctor.

BEFORE TAKING THIS MEDICATION:

You should not use this medicine if you are allergic to triazolam or similar medicines (such as alprazolam, diazepam, lorazepam, Valium, Xanax, Versed, Klonopin, and others).

Some drugs should not be used with triazolam. Your treatment plan may change if you also use:

  • nefazodone;

  • cancer medicine;

  • an antibiotic or antifungal medicine; or

  • antiviral medicine to treat HIV or hepatitis C.

Tell your doctor if you have ever had:

  • depression, mental illness, suicidal thoughts or actions;

  • lung disease, breathing problems, sleep apnea (breathing stops during sleep); or

  • alcoholism or drug addiction.

If you use triazolam during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

You should not breastfeed within 28 hours after using triazolam. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

If you do breastfeed, tell your doctor if you notice drowsiness, breathing problems, or feeding problems in the nursing baby.

Not approved for use by anyone younger than 18 years old.


SIDE EFFECTS

Dizziness or difficulty with coordination may occur. If either of these effects lasts or gets worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness or falling, get up slowly when rising from a sitting or lying position.

This medication may make you sleepy during the day. Tell your doctor if you have daytime drowsiness. Your dose may need to be adjusted.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: memory loss, mental/mood/behavior changes (such as new/worsening depression, abnormal thoughts, thoughts of suicide, hallucinations, confusion, agitation, aggressive behavior, anxiety).

Rarely, after taking this drug, people have gotten out of bed and driven vehicles while not fully awake ("sleep-driving"). People have also sleepwalked, prepared/eaten food, made phone calls, or had sex while not fully awake. Often, these people do not remember these events. This problem can be dangerous to you or to others. If you find out that you have done any of these activities after taking this medication, tell your doctor right away. Your risk is increased if you use alcohol or other medications that can make you drowsy while taking triazolam.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.


 

Usual Adult Dose for Insomnia:
Source: https://www.drugs.com/mtm/triazolam.html#dosage

Initial dose: 0.25 mg orally once a day at bedtime
Maintenance dose: 0.125 to 0.25 mg orally once a day at bedtime
Maximum dose: 0.5 mg/day
Duration of therapy: 7 to 10 days

Comments: 
-Failure to respond after 7 to 10 days may suggest a primary psychiatric and/or medical illness that requires further evaluation.
-Use of this drug for more than 2 to 3 weeks requires complete reevaluation of the patient.

Use: Short-term treatment of insomnia

Usual Geriatric Dose for Insomnia:

Initial dose: 0.125 mg orally once a day at bedtime
Maintenance dose: 0.125 to 0.25 mg orally once a day at bedtime
Maximum dose: 0.25 mg/day
Duration of therapy: 7 to 10 days

Comments:
-Failure to respond after 7 to 10 days may suggest a primary psychiatric and/or medical illness that requires further evaluation.
-Use of this drug for more than 2 to 3 weeks requires complete reevaluation of the patient.
-The lowest effective dose should be used to minimize the potential for oversedation.

Use: Short-term treatment of insomnia

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